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Kemadrin (procyclidine) is a drug substance similar in action to atropine. It used to reduce tremor and muscle stiffness in parkinsonism.


The active ingredient of the drug – procyclidine – is used to reduce unwanted side effects caused by certain antipsychotic drugs. Antipsychotic medications are prescribed for mental disorders such as schizophrenia. As a side effect of treatment, antipsychotic medications can sometimes cause unwanted body movements, some of which can be serious. These motor disorders are often referred to as “extrapyramidal side effects” or “parkinsonism” and include such reactions as uncontrolled movements of the face and body, tremors and anxiety. Kemadrin is prescribed to relieve these types of symptoms.

The drug is also used to relieve some symptoms of Parkinson’s disease, which include movement problems, such as muscle stiffness, tremors and eye movements, and sweating and too much saliva.

Instructions for use

Before taking the drug, read the manufacturer’s printed information sheet. The manufacturer’s leaflet will provide you with more information about this medicine and a complete list of side effects that may occur while taking it.

Take the pills exactly as directed by your doctor. It is usually recommended to take the pills three times a day, but you may be advised to take it more or less often.

The pills are taken regardless of meals, although sometimes it is recommended to take them with meals to help prevent nausea.

Try taking the pills at the same time every day.

If you missed the pill, take it as soon as possible. If it is time for the next dose, just skip the missed pill. Do not take two pills together.


Do not take Kemadrin if you have any of the following conditions:

  • pregnancy, breastfeeding;
  • liver or kidney problems
  • trouble urinating.
  • constipation for more than a week
  • high blood pressure in your eyes (for example, glaucoma).
  • hypertension.
  • heart or blood vessel problems
  • prostate problems
  • muscle weakness (myasthenia gravis).
  • psychosis.
  • use of other medicines
  • an allergic reaction to procyclidine in the past.

Side effects

The most common side effects caused by Kemadrin are dry mouth, constipation, blurred vision, difficulty urinating, dizziness, rapid heartbeat, skin rash, mood changes, and anxiety.

If you have any severe and/or long-lasting adverse reactions after taking the drug, stop taking the pills and consult your doctor.